Okan Tanrıverdi1, Lütfü Aşkın1, Alper Serçelik2
1Department of Cardiology, Adıyaman University Faculty of Medicine, Adıyaman, Turkey
2Department of Cardiology, Sanko Üniversity Faculty of Medicine, Gaziantep, Turkey
Keywords: Carotid intima-media thickness, levated blood pressure, non-dipping status
Objectives: This study aims to evaluate the relationship between non-dipping pattern and carotid intima-media thickness (CIMT) in patients with elevated blood pressure (BP).
Patients and methods: Between November 2019 and April 2019, a total of 150 consecutive patients (84 males, 66 females; mean age 52.3±10.1 years; range, 40 to 65 years) with elevated BP (systolic BP between 120 and 129 mmHg and diastolic BP less than 80 mmHg) were included. The patients were divided into two groups as the dipper (n=92) and non-dipper (n=58) groups according to the ambulatory BP measurements. The CIMT was measured using ultrasonography and compared between the groups.
Results: The CIMT was significantly higher in the non-dipper group (0.7±0.2 mm vs. 1.0±0.2 mm, respectively; p<0.001). The CIMT was an independent predictor of non-dipping pattern in the multivariate logistic regression analysis (odds ratio: 1.098, 95% confidence interval: 1.062-1.135; p<0.001).
Conclusion: Our study results show that the non-dipping status is closely associated with the known indicator for atherosclerosis such as
CIMT in elevated blood pressure category.