Cardiovascular Surgery and Interventions
2024, Vol 11, Num 3 Page(s): 213-216
| Back | Table of Contents | Full Text | PDF | Similar Articles | |
An interesting case of refractory hypotension and noncardiogenic pulmonary edema after amlodipine overdose
İhsan Alur1, Gökhan Peker2, Taner Taşyüz2, Ahmet Deniz Kaya3, Osman Kaya4
1Department of Cardiovascular Surgery, Private Egekent Hospital, Denizli, Türkiye
2Department of Anesthesiology and Reanimation, Private Egekent Hospital, Denizli, Türkiye
3Department of Cardiovascular Surgery, Ministry of Health, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Türkiye
4Department of Anesthesiology and Reanimation, Ministry of Health, Nizip State Hospital, Gaziantep, Türkiye
Keywords: Amlodipine, hemodialysis, hemofiltration, intoxication, overdoze, ultrafiltration
Amlodipine is a dihydropyridine calcium channel blocker that acts on intravascular L-type calcium channels. It is most effective on vascular smooth muscle cells and has little effect on cardiac tissue. Its most common use is hypertension, angina, arrhythmias, subarachnoid hemorrhage, migraine, and Raynaud's disease. Amlodipine is preferred because it is used once a day and has minimal side effects on heart rate. However, in case of acute overdose, either accidental or deliberate (e.g., suicide attempts), dangerous side effects may occur and may result in death. Herein, we presented a 34-year-old male patient who ingested 90 tablets of amlodipine 10 mg and was successfully treated.
İhsan Alur1, Gökhan Peker2, Taner Taşyüz2, Ahmet Deniz Kaya3, Osman Kaya4
1Department of Cardiovascular Surgery, Private Egekent Hospital, Denizli, Türkiye
2Department of Anesthesiology and Reanimation, Private Egekent Hospital, Denizli, Türkiye
3Department of Cardiovascular Surgery, Ministry of Health, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Türkiye
4Department of Anesthesiology and Reanimation, Ministry of Health, Nizip State Hospital, Gaziantep, Türkiye
Keywords: Amlodipine, hemodialysis, hemofiltration, intoxication, overdoze, ultrafiltration
Amlodipine is a dihydropyridine calcium channel blocker that acts on intravascular L-type calcium channels. It is most effective on vascular smooth muscle cells and has little effect on cardiac tissue. Its most common use is hypertension, angina, arrhythmias, subarachnoid hemorrhage, migraine, and Raynaud's disease. Amlodipine is preferred because it is used once a day and has minimal side effects on heart rate. However, in case of acute overdose, either accidental or deliberate (e.g., suicide attempts), dangerous side effects may occur and may result in death. Herein, we presented a 34-year-old male patient who ingested 90 tablets of amlodipine 10 mg and was successfully treated.
DOI : 10.5606/e-cvsi.2024.1717
| Back | Table of Contents | Full Text | PDF | Similar Articles | |