Cardiovascular Surgery and Interventions 2020, Vol 7, Num 2 Page(s): 076-083
Association between non-dipping status and carotid intima-media thickness in patients with elevated blood pressure category

Okan Tanrıverdi1, Lütfü Aşkın1, Alper Serçelik2

1Department of Cardiology, Adıyaman University Faculty of Medicine, Adıyaman, Turkey
2Department of Cardiology, Sanko Üniversity Faculty of Medicine, Gaziantep, Turkey

Keywords: Carotid intima-media thickness, levated blood pressure, non-dipping status
Objectives: This study aims to evaluate the relationship between non-dipping pattern and carotid intima-media thickness (CIMT) in patients with elevated blood pressure (BP).

Patients and methods: Between November 2019 and April 2019, a total of 150 consecutive patients (84 males, 66 females; mean age 52.3±10.1 years; range, 40 to 65 years) with elevated BP (systolic BP between 120 and 129 mmHg and diastolic BP less than 80 mmHg) were included. The patients were divided into two groups as the dipper (n=92) and non-dipper (n=58) groups according to the ambulatory BP measurements. The CIMT was measured using ultrasonography and compared between the groups.

Results: The CIMT was significantly higher in the non-dipper group (0.7±0.2 mm vs. 1.0±0.2 mm, respectively; p<0.001). The CIMT was an independent predictor of non-dipping pattern in the multivariate logistic regression analysis (odds ratio: 1.098, 95% confidence interval: 1.062-1.135; p<0.001).

Conclusion: Our study results show that the non-dipping status is closely associated with the known indicator for atherosclerosis such as CIMT in elevated blood pressure category.

DOI : 10.5606/e-cvsi.2020.845