Cardiovascular Surgery and Interventions 2020, Vol 7, Num 3 Page(s): 129-135
Factors associated with medication non-adherence among patients on hemodialysis: A cross-sectional study

Ülkü Nur Kırman1, Betül Nur Keser1, Cemal Kocaaslan2, Ebuzer Aydın2

1Faculty of Medicine, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey
2Department of Cardiovascular Surgery, Faculty of Medicine, Istanbul Medeniyet University, Göztepe Training and Research Hospital, Istanbul, Turkey

Keywords: Hemodialysis, knowledge, medication non-adherence, motivation
Objectives: In this study, we aimed to evaluate the factors associated with medication non-adherence in terms of motivation and knowledge levels among hemodialysis-dependent patients.

Patients and methods: Between March 2018 and April 2018, 134 Caucasian patients (78 males, 56 females; mean age 64.1±13.0 years; range, 23 to 86 years) on hemodialysis at two dialysis centers were included in this cross-sectional study. The Modified Morisky Scale was administered to assess the patients’ levels of motivation and knowledge about their medications.

Results: The mean time on hemodialysis was 52.3±50.8 months and the mean number of prescribed medications was 7.5±3.5. The ratio of patients with a low level of motivation and knowledge were 17.2% and 11.9%, respectively. Hypertension was found to be an independent risk factor for low level of motivation (adjusted odds ratio [aOR]: 5.260 [95% confidence interval [CI]: 1.122-24.665], p=0.035). Being employed was found to be an independent risk factor for low level of knowledge (aOR: 5.000 [95% CI: 0.404-6.219], p=0.01).

Conclusion: Hypertension and being employed were found to be associated factors of non-adherence to medication therapy. Healthcare professionals should recognize the factors associated with non-adherence and perform effective interventions to prevent adverse outcomes of non-adherence among patients receiving hemodialysis.

DOI : 10.5606/e-cvsi.2020.924