Cardiovascular Surgery and Interventions 2022, Vol 9, Num 1 Page(s): 020-026
The effect of hemodialysis on left ventricular global longitudinal strain in chronic hemodialysis patients with preserved left ventricular ejection fraction

Oktay Şenöz1, Gökhan Atay2, Ferhat Siyamend Yurdam1, Zeynep Yapan Emren1, Ahmet Erseçgin1, Hayri Üstün Arda2

1Department of Cardiology, Izmir Bakırçay University, Izmir, Turkey
2Department of Nephrology, Izmir Bakırçay University, Izmir, Turkey

Keywords: End-stage renal disease, global longitudinal strain, hemodialysis, speckle-tracking echocardiography
Objectives: In the present study, we aimed to evaluate the acute effects of hemodialysis (HD) on left ventricular functions with left ventricular (LV) global longitudinal strain (GLS).

Patients and methods: This prospective study included a total of 38 patients (24 males, 14 females; mean age: 60.8±13.8 years; range, 31 to 82 years) who were on chronic HD for at least six months and had a LV ejection fraction of ≥50% between December 2021 and January 2022. The clinical and echocardiographic features of the patients were recorded before and after HD. The GLS was calculated using two-dimensional speckle-tracking method.

Results: The mean dialysis time of the patients was 6.3±3.9 years. The left atrial volume index was significantly lower after HD than before (30.1±10.0 vs. 27.5±8.2 mL/m2, p=0.005). Pulsed Doppler echocardiography showed significantly decreased E and A wave peak velocity after HD (99.3±38.2 vs. 80.4±27.8 cm/s, p=0.001 and 99.4±23.2 vs. 90.4±25.5 cm/s, p=0.022), but no significant change in the E/A ratio (1.1±0.5 vs. 1±0.6, p=0.660). There was no significant change on the LV GLS between before and after HD (-17.3±2.6 vs. -16.9±2.6%, p=0.088).

Conclusion: Hemodialysis has no significant effect on LV GLS in the acute phase in patients with end-stage chronic renal disease.

DOI : 10.5606/e-cvsi.2022.1258