Cardiovascular Surgery and Interventions 2024, Vol 11, Num 2 Page(s): 080-086
Relationship between cryptogenic ischemic stroke and P wave peak time

Emin Koyun1, İlhan Koyuncu2, Ferhat Dindaş3, Mustafa Doğduş4, Levent Öcek5

1Department of Cardiology, Sivas Numune Hospital, Sivas, Türkiye
2Department of Cardiology, Bakırçay University, Çiğli Training and Research Hospital, İzmir, Türkiye
3Department of Cardiology, Uşak University Training and Research Hospital, Uşak, Türkiye
4Department of Cardiology, İzmir University of Economics, Faculty of Medicine, Medical Point Hospital, İzmir, Türkiye
5Department of Neurology, Health Sciences University Izmir Faculty of Medicine, İzmir, Türkiye

Keywords: Electrocardiography, cryptogenic ischemic stroke, P wave peak time, atrial fibrillation
Objectives: This study aimed to examine whether P wave peak time (PWPT), a predictor of atrial fibrillation (AF), is significantly higher at the time of diagnosis in cryptogenic ischemic stroke patients.

Patients and methods: The retrospective was conducted with 118 individuals (72 males, 46 females; mean age: 66.4±13.8 years) with cryptogenic ischemic stroke in the patient group and 118 individuals (77 males, 41 females; mean age: 63.2±16.1 years) without cerebrovascular disease in the control group between January 2021 and December 2023. The groups were compared regarding PWPT.

Results: As a result of multivariate regression analysis, PWPT-D2 and PWPT-V1 were found to be independent predictors of cryptogenic ischemic stroke. In the ROC analysis, when PWPT-D2 was >51.5 msec, the sensitivity for the diagnosis of cryptogenic ischemic stroke was found to be 80%, and the specificity was 76%. When PWPT-V1 was >46 msec, the sensitivity for the diagnosis of cryptogenic ischemic stroke was found to be 75%, and the specificity was 73%.

Conclusion: P wave peak time is an important predictor of cryptogenic ischemic stroke. The reason for the high PWPT level in these patients may be undetected AF. Therefore, longer-term rhythm Holter may be recommended in these patients.

DOI : 10.5606/e-cvsi.2024.1654