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Musa İlker Durak1, Ahmet Ünalır2
1Department of Cardiology, Etlik City Hospital, Ankara, Türkiye
2Department of Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Türkiye
Keywords: Acute coronary syndrome, Killip-Kimball Classification, neutrophil count, ST elevation myocardial infarction
Objectives: The study aimed to assess the correlation between neutrophil count at admission and during the short-term follow-up period with clinical outcomes in individuals presenting with ST-elevation myocardial infarction (STEMI).
Patients and methods: This prospective study was conducted between March 2010 and September 2010. Seventy-two patients (58 males, 14 females; mean age: 67±12 years; range, 50 to 89 years) diagnosed with acute coronary syndrome presenting with STEMI were included in the study. Complete blood count, serum glucose, urea, creatinine levels, and glomerular filtration rate were assessed in patients at 0, 4, 24, and 48 h. Patients were stratified according to the Killip-Kimball classification. Adverse clinical outcomes were defined as death, reinfarction, and cerebrovascular disease.
Results: Adverse clinical outcomes were significantly higher in patients with higher age and Killip-Kimball scores (p=0.04, p<0.01). A correlation was identified between the white blood cell (WBC) count at 48 h (p=0.04) and the neutrophil count at all time points with adverse clinical outcomes (p<0.05).
Conclusion: In our study, a correlation was determined between WBC and neutrophil counts and the rates of in-hospital mortality and
adverse clinical outcomes in individuals presenting with acute STEMI. Elevated neutrophil count assessed upon admission to the hospital
and during short-term follow-up may be utilized to identify high-risk patients.
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