| Comment on: The utility of vitamin D levels in predicting the severity of coronary artery disease in obese patients | |
| DOI: 10.5606/e-cvsi.2025.1868 | |
| Mert Çelik | |
| Department of Cardiovascular Surgery, Muş State Hospital, Muş, Türkiye | |
I read with interest the article titled "The utility of
vitamin D levels in predicting the severity of coronary
artery disease in obese patients" by Candemir et al.,[1]
published in the journal Cardiovascular Surgery and
Interventions. This cross-sectional study investigates
the relationship between vitamin D (25-hydroxy
[OH]D, 25[OH]D) levels and the severity of coronary
artery disease (CAD) in obese patients undergoing
coronary angiography due to stable angina pectoris,
using the SYNTAX score. The data obtained from
the study indicate that in obese patients with vitamin
D deficiency, the severity of CAD increases in relation
to higher SYNTAX scores. However, I believe several
points need to be addressed. I believe it is necessary to provide information about the patients undergoing coronary angiography due to stable angina pectoris, such as their previous coronary angiography history, stent history, and current medical treatments. Additionally, the effects of current treatments on vitamin D levels should also be considered. There is extensive literature on the effects of statins, which are frequently used in the treatment of CAD, on vitamin D levels. Therefore, I believe the current medical treatments of the patients should also be taken into consideration. Additionally, climate and sun exposure time significantly contribute to vitamin D production. Hence, I believe that these findings could be further expanded through multicenter studies examining potential connections between climate, sun exposure time, and vitamin D production. Additionally, as the authors have also mentioned, I believe that increasing the number of patients will lead to more valuable data. In conclusion, the study by Candemir et al. suggests that more severe CAD is observed in obese individuals. The fact that vitamin D deficiency may be an independent predictor of CAD severity in this population is very valuable. I congratulate the authors and look forward to future research on this topic and hope that the authors will consider my suggestions in their future work. Data Sharing Statement: The data that support the findings of this study are available from the corresponding author upon reasonable request. Conflict of Interest: The author declared no conflicts of interest with respect to the authorship and/or publication of this article. Funding: The author received no financial support for the research and/or authorship of this article. |
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